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Some medicines may affect how premarin vaginal cream works.

Information about Premarin.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Before using this medicationtell your doctor or pharmacist your medical historyespecially ofvaginal bleeding of unknown causecertain cancerssuch as breast cancercancer of the uterus/ovariesblood clotsstrokeheart diseasesuch as heart attackliver diseasekidney diseasefamily medical historyespecially breast lumpscancerblood clotsangioedemablood clotting disorderssuch as protein C or protein S deficiencyhigh blood pressurediabeteshigh cholesterol/triglyceride levelsobesitylupusunderactive thyroidhypothyroidismmineral imbalancelow or high level of calcium in the blooda certain hormone problemhypoparathyroidismuterus problemssuch as fibroidsendometriosisgallbladder diseaseasthmaseizuresmigraine headachesa certain blood disorderporphyriamental/mood disorderssuch as dementiadepression

If pregnancy occurs during medication with Premarin treatment should be withdrawn immediatelyThe results of most epidemiological studies to date relevant to inadvertent foetal exposure to estrogens indicate no teratogenic or foetotoxic effects.

Estrogenseither used alone or with another hormoneprogestinhave rarely caused very serious side effectsDiscuss the risks and benefits of hormone treatment with your doctorEstrogens should not be used to prevent heart disease or dementia.

High levels of calcium in your bloodnauseavomitingconstipationincreased thirst or urinationmuscle weaknessbone painlack of energy.

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conjugated estrogen is the active ingredient present in premarin.