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Clozaril also acts as an antagonist at adrenergic, cholinergic, histaminergic and serotonergic receptors.

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The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may affect the heart rhythmBefore using clozapinetell your doctor or pharmacist of all the drugs you take and if you have any of the following conditionscertain heart problemsheart failureslow heartbeatQT prolongation in the EKGfamily history of certain heart problemsQT prolongation in the EKGsudden cardiac death

This medication is used to treat certain mental/mood disordersschizophreniaschizoaffective disordersClozapine is a psychiatric medicationanti-psychotic typethat works by helping to restore the balance of certain natural substancesneurotransmittersin the brain.

Generic NameclozapineKLOE za peenBrand NamesClozarilFazaCloVersaclozClopineCloZAPine SynthonDenzapineZaponex.

Clozaril can lower blood cells that help your body fight infectionsespecially in women and older adultsand in people who are malnourished or have serious medical problemsThis can make it easier for you to develop a serious or life-threatening infectionYour blood will need to be tested oftenYour future treatments may be delayed based on the results of these tests.

Kidney problemslittle or no urinationswelling in your feet or anklesfeeling tired or short of breath;

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when treatment with clozaril clozapine is discontinued regardless of the reason , wbc count and anc must be monitored weekly for at least 4 weeks from the day of discontinuation or until wbc 3500 mm 3 and anc 2000 mm 3.